3 edition of Aging, sex, and DNA repair found in the catalog.
Aging, sex, and DNA repair
Includes bibliographical references and index.
|Statement||Carol Bernstein, Harris Bernstein.|
|LC Classifications||QP86 .B34 1991|
|The Physical Object|
|Pagination||xii, 382 p. :|
|Number of Pages||382|
|LC Control Number||90014467|
Research into extending humanity’s healthy lifespan has been progressing rapidly in recent years. In February, a group of aging and longevity scientists founded a nonprofit to foster the work and serve as a resource for governments and businesses looking to understand the potentially far-reaching implications of a population that lives significantly longer, healthier lives. The ripening of animate being encephalon and tissue is a major cause of functional diminution in old age and is a causative agent of many diseases like Alzheimer 's and Pakinson 's disease. The DNA fix mechanism maintains the genome stableness. Many map like oxidization emphasis (old age) reduced mitochondrial maps, toxic by-product s harm to DNA.
See a sex therapist. A therapist may be able to help you and your partner with specific concerns. Ask your doctor for a referral. Expand your definition of sex. Intercourse is only one way to have a fulfilling sex life. Touching, kissing and other intimate contact can be rewarding for you and your partner. The Janus face of DNA methylation in aging. Age-associated alterations in the DNA either due to oxidative damage, defects in DNA repair or epigenetic modifications such as methylation that lead to mutations and changes in the expression of genes are thought to be partially responsible.
MIT neuroscientists have discovered that an enzyme called HDAC1 is critical for repairing age-related DNA damage to genes involved in memory and other cognitive functions. HDAC1 is often diminished in both Alzheimer’s patients and in normally aging adults, and the study suggests restoring it could have positive benefits for both g: sex. The test involves cutting yeast telomeres and then observing them to catch any repair mechanisms going on. An enzyme called ATM Kinase normally involved with DNA repair has been suspected for some time to help lengthen telomeres as well, and after the new test was perfected they tested this new enzyme for g: sex.
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This book provides an integrated explanation of aging and sex based on current knowledge of DNA damage and repair. Show less Why organisms age and why sexual reproduction exists are major unsolved problems in biology.
Aging, Sex, and DNA Repair - Kindle edition by Author Unknown. Download it once and read it on your Kindle device, PC, phones or tablets. Use features like bookmarks, note taking and highlighting while reading Aging, Sex, and DNA Repair. Aging, Sex, and DNA Repair Paperback – Novem by Carol Bernstein (Author) See all 4 formats and editions Hide other formats and editions.
Price New from Used from eTextbook "Please retry" $ — Cited by: Description Why organisms age and why sexual reproduction exists are major unsolved problems in biology. This book provides an integrated explanation of aging and sex based on current knowledge of DNA damage and Edition: 1.
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Aging, sex, and DNA repair by Bernstein, Carol, Pages: Summary: Discusses the universality of the problem of DNA damage, and meiosis as sex adaptation for DNA repair. The authors describe ageing as a consequence of accumulated DNA damage, and explore mating, in eukaryotes, as an mdaptation for masking mutation.
Why organisms age and why sexual reproduction exists are major unsolved problems in biology. This book provides an integrated explanation of aging and sex based on current knowledge of DNA damage and repair. Abstract A number of theories have been proposed to account for the biological phenomena of aging and sexual reproduction (sex).
An emerging unified theory that accounts for a considerable amount o Aging and Sex, DNA Repair in - Bernstein - - Major Reference Works - Wiley Online Library Skip to. Journals & Books; Help There are many outstanding questions regarding the connection between DNA repair and aging that will benefit from the application of emerging techniques in molecular biology and genetics.
In models of premature aging, the most vulnerable system fails first, leading to death and precluding gain of insights from effects Missing: sex.
Furthermore, the measured DNA damage could reflect changes in the causative factors, and/or changes in DNA protection and/or changes in DNA repair capacity.
It must also be noted that the type of cell and tissue used could reflect different aging rates within the organism. Since DNA repair and DNA damage response are tightly controlled processes it is tempting to speculate that DNA damage response becomes less efficient or somewhat disregulated with age.
Indeed, alterations in the response of DNA repair proteins to DNA damage have also been reported (40–42. DNA Damage, DNA Repair, Aging, and Neurodegeneration Scott Maynard1, Evandro Fei Fang 2, Morten Scheibye-Knudsen, Deborah L.
Croteau, and Vilhelm A. Bohr1,2 1Department of Cellular and Molecular Medicine, Center for Healthy Aging, University of Copenhagen, DK Copenhagen, Denmark 2Laboratory of Molecular Gerontology, National Institute on Aging, National Institutes of Missing: sex. This book illustrates the activities of mammalian sirtuin SIRT6 in connection with DNA damage repair and premature aging.
It mainly presents research on the nuclear lamin A, notably the upregulation of p53 and acetylation etc. Taken together, these studies reveal the various regulatory roles of SIRT6, which are of substantial biological relevance in DNA damage repair, aging and longevity, and Missing: sex.
The roles of DNA damage and DNA repair in cancer and aging. A mutation is a change in the DNA sequence in which normal base pairs are substituted, added, deleted or rearranged.
The DNA containing a mutation still consists of a sequence of standard base pairs, and the altered DNA sequence can be copied when the DNA is replicated.
Not all mismatch repair homologs have a role in DNA repair. Similar to the situation in budding yeast, the C. elegans MutS family homologs, him/msh-4 and msh-5 have no apparent role in repair, but have a specialized role in crossing over during meiosis.
DNA Repair "DNA repair" refers to a collection of processes by which the human body identifies and corrects damage to its own DNA molecules.
In human cells, exposure to abnormal, destructive environmental factors (eg.-UV light/radiation, toxic chemicals, poor nutrition, genetically modified foods-GMOs etc), along with even normal daily metabolic activity, can cause DNA damage.
The DNA damage theory of aging proposes that aging is a consequence of unrepaired accumulation of naturally occurring DNA in this context is a DNA alteration that has an abnormal structure.
Although both mitochondrial and nuclear DNA damage can contribute to aging, nuclear DNA is the main subject of this analysis.
Nuclear DNA damage can contribute to aging either indirectly (by Missing: sex. Aging is defined as the time-dependent decline of functional properties.
One common denominator of aging is mitochondrial dysfunction and accumulation of genetic damage throughout life. In fact, the imperfect maintenance of nuclear and mitochondrial DNA likely represents a critical contributor of aging.
Each day, the integrity and stability of DNA are challenged by exogenous Missing: sex. Harvard Scientists discovered a way to repair DNA damage and reverse cellular aging. We asked the authors of the study what this could mean for your g: sex.
The fact that this one genetic defect results in so many aging-like changes suggests that impaired DNA repair mechanisms may be responsible for some aspects of the aging process in healthy. "The issues of the body from desire to aging, as well as those of identity and cultural imprinting, have been at the core of my concerns.
The carnal nature of paint has seemed to me a perfect metaphor, the specifics of image, a necessary elaboration. The last 45 years of work, I think, reveal my ongoing interest in both process and relevance.".Bernstein C, Bernstein H.
Aging, Sex, and DNA Repair. Academic Press; San Diego, CA: J A study just out shows that as we get older, our DNA changes. A lot. Researchers in Iceland and the U.S.
showed that over a period of years, some people's DNA changed as much as 20%. These differences aren't in the famous A, T.